Total Parenteral Nutrition-associated Cholestasis: Prematurity or Amino Acids?
نویسندگان
چکیده
منابع مشابه
Parenteral nutrition associated cholestasis
Parenteral nutrition (PN) is life saving for many preterm infants and other neonates with severe illness, but prolonged use of PN can lead to intrahepatic cholestasis, referred to as parenteral nutrition–associated cholestasis (PNAC). It is defined as direct bilirubin greater than 2.0 mg/dL persistent for at least 2 consecutive tests duringthe administration of PN, not associated with other kno...
متن کاملParenteral Nutrition: Amino Acids
There is growing interest in nutrition therapies that deliver a generous amount of protein, but not a toxic amount of energy, to protein-catabolic critically ill patients. Parenteral amino acids can achieve this goal. This article summarizes the biochemical and nutritional principles that guide parenteral amino acid therapy, explains how parenteral amino acid solutions are formulated, and compa...
متن کاملEffect of S-adenosylmethionine on total parenteral nutrition-associated cholestasis
Methods: Twenty-four newborn rabbits were randomly divided into 3 groups: normal control group receiving breast milk, TPN group receiving TPN at a dose of 200 kcal/kg per day, and SAMe group receiving TPN plus SAMe at an intravenous dose of 100 mg/kg per day. Blood and liver samples were collected one week later. The levels of serum bile acid, alanine aminotransferase (ALT), alkaline phosphatas...
متن کاملTotal Parenteral Nutrition – Associated Cholestasis (TPNAC) in Newborns
Pediatrics Gastroenterologist & Master in Clinical Nutrition, Chief of Pediatrics Gastroenterology, Hepatology and Nutrition Department, Clínica del Niño PREVIANDES & Professor of Pediatric Gastroenterology & Pediatric Department Universidad El Bosque, Master in Clinical Nutrition and Professor of Pediatric Gastroenterology & Pediatric Department Universidad El Bosque, Pediatrician visitors Cor...
متن کاملChylothorax or leakage of total parenteral nutrition?
The diagnosis chylothorax is based on a chemical analysis of the pleural effusion. According to the literature, this analysis can be rather straightforward, comprising measurements of triglycerides, chylomicrons, and cholesterol. In this report we present an autopsy case that alerted us to interpret these results critically. Although the laboratory tests of the pleural effusion in this patient ...
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ژورنال
عنوان ژورنال: Journal of Perinatology
سال: 2003
ISSN: 0743-8346,1476-5543
DOI: 10.1038/sj.jp.7210989